Lois has Alzheimer's disease. She and her daughter Linda provided care for Lois's mother Leona when she had severe Alzheimer's disease. Now Linda, age 57, is showingsigns of impaired memory. Linda's daughter Lucy is pregnant with her first child and has contacted a genetic counselor to discuss Alzheimer's risk in her family. Who in this family is the proband?

Question

Quizplus · Accepted Answer

The proband is the person within a family who brought the potential genetic issue to the attention of a health-care professional or genetics professional. Lucy, even though she does not have Alzheimer's but wishes to discuss whether the disorder has a genetic component because three related parental individuals have expressed the problem, is the proband.

Lois Has Alzheimer's Disease