What is the expected outcome of pregnancy for women with phenylketonuria (PKU) when the blood levels of phenylalanine are high throughout the pregnancy?

Question

Quizplus · Accepted Answer

With increasing life spans and cognition among people with PKU, a newer issue is the problem of an increased incidence of a variety of health problems and birth defects among infants born to PKU mothers. The infants do not have PKU; however, abnormal blood levels of amino acids, especially during embryonic life, result in a wide variety of birth defects, most commonly of the cardiovascular system. The best pregnancy outcomes for PKU mothers are achieved when phenylalanine levels are well controlled before, as well as during, pregnancy.

What Is the Expected Outcome of Pregnancy for Women with Phenylketonuria