Which specific type of genetic problem causes sickle cell disease?

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Sickle cell disease (SCD) is a genetic disorder caused by a single-nucleotide polymorphism in both alleles of a single gene, which results in the abnormal formation of the beta chain of hemoglobin (beta globin). In the classic form of sickle cell disease, both beta-globin alleles have a mutation in which the DNA triplet coding for glutamic acid has adenine substituted for thymine (instead of CTC, the triplet now reads CAC). This mutation results in valine as the sixth amino acid in the protein sequence. There is no deletion of introns or exons, nor is there a translocation (balanced or unbalanced).

Which Specific Type of Genetic Problem Causes Sickle Cell Disease