Which cancer type is associated with a 9;22 translocation t(9;22)?

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Quizplus · Accepted Answer

As cancer cells become more malignant, they usually become aneuploid, with gains or losses of whole chromosomes, chromosome breakage, and the structural rearrangements of chromosomes. Some chromosomal rearrangements are unique to a cancer type and can be used to identify it as a specific cancer type. A chromosome rearrangement in which the ends of the q arms of chromosome 22 are translocated to the q arms of chromosome 9 results in the activation of a special tyrosine kinase that converts bone marrow cells into chronic myelogenous leukemia.

Which Cancer Type Is Associated with a 9;22 Translocation T(9;22)