How does an MSH 2 gene mutation contribute to the development of colon cancer?

The MSH 2 gene is a DNA repair gene. When it is mutated, damaged DNA is either incorrectly repaired or not repaired. This problem can result in either mutations in suppressor genes or mutations in oncogenes. In either case, oncogene expression is increased, and cell growth is unregulated.

How does an MSH 2 gene mutation contribute to the development of colon cancer?

The MSH 2 gene is a DNA repair gene. When it is mutated, damaged DNA is either incorrectly repaired or not repaired. This problem can result in either mutations in suppressor genes or mutations in oncogenes. In either case, oncogene expression is increased, and cell growth is unregulated.

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How Does an MSH₂gene Mutation Contribute to the Development

Question 7

Multiple Choice

How does an MSH<sub>2 </sub>gene mutation contribute to the development of colon cancer?

How does an MSH₂gene mutation contribute to the development of colon cancer?

A) Suppressor gene function is enhanced.
B) DNA mutations are incorrectly repaired.
C) Trinucleotide repeat sequences are enhanced.
D) Drug resistance genes undergo amplification.

Correct Answer: