When nitric oxide is used in the dilation of smooth muscle cells,which of the following would interfere with the relaxation of the smooth muscle cells? Inhibitors of
A)calcium release by the ER.
B)nitric oxide.
C)guanylyl cyclase.
D)calmodulin.
E)all of the above

Question

Quizplus · Accepted Answer

Nitric oxide causes relaxation of smooth muscle cells by increasing cGMP levels, which in turn inhibits calcium release from the ER and inhibits calmodulin. Inhibitors of any of these steps would interfere with the relaxation of the smooth muscle cells.

When Nitric Oxide Is Used in the Dilation of Smooth