Mice lacking the ability to make caspase-9 die as the result of numerous defects.During the necropsy (animal autopsy)of the animal you note that the brains of these mice are
A)unregulated growth of the nerve cells.
B)lack of apoptosis of some cells.
C)overstimulation of G-protein-mediated transduction.
D)overproduction of the Etr1 receptor protein.
E)all of the above

Question

Quizplus · Accepted Answer

Mice lacking caspase-9, a key component of apoptotic cell death, would likely have a defect in the ability to undergo programmed cell death. As a result, some cells that should be eliminated during development or in response to damage or stress may persist, leading to developmental defects or disease. The brain is particularly susceptible to such defects, as precise regulation of cell death is important for proper development and function. Therefore, it is likely that the brains of these mice would have a lack of apoptosis in some cells. Unregulated growth of nerve cells, overstimulation of G-protein-mediated transduction, and overproduction of the Etr1 receptor protein are not necessarily related to caspase-9 function and would not be expected to occur in all mice lacking this gene.

Mice Lacking the Ability to Make Caspase-9 Die as the Result