An agent that would work well as an antibiotic against prokaryotic infection would target the
A)50S large ribosomal subunit.
B)RNA polymerase II.
C)40S small ribosomal subunit.
D)DNA polymerase.
E)mitochondria.

Question

Quizplus · Accepted Answer

The 50S large ribosomal subunit is essential for protein synthesis in prokaryotic cells. Therefore, targeting this subunit with an antibiotic would prevent the bacteria from making essential proteins and ultimately lead to their death. Antibiotics like erythromycin and chloramphenicol target the 50S subunit and have been effective against a wide range of bacterial infections. Options B, C, D, and E are not effective targets for antibiotics against prokaryotic infections. RNA polymerase II is found in eukaryotic cells, not prokaryotes, and is involved in eukaryotic gene transcription. The 40S small ribosomal subunit is present in eukaryotic cells and plays a role in translation initiation. DNA polymerase is involved in DNA replication and repair and is also found in eukaryotes. Mitochondria are organelles found in eukaryotic cells and are not present in prokaryotes.

An Agent That Would Work Well as an Antibiotic Against