Messenger RNAs containing premature stop codons are destroyed by the mechanism of
A)nonstop decay.
B)directed RNase activity.
C)nonsense-mediated decay.
D)error-mediated repair.
E)none of the above

Question

Quizplus · Accepted Answer

Messenger RNAs containing premature stop codons undergo nonsense-mediated decay, which is a cellular mechanism that ensures the elimination of mRNA transcripts that contain premature stop codons. These transcripts are recognized by the cell's surveillance system, which targets them for destruction. Nonstop decay and directed RNase activity are not the mechanisms involved in the degradation of mRNAs with premature stop codons, while error-mediated repair is not a relevant mechanism for RNA degradation.

Messenger RNAs Containing Premature Stop Codons Are Destroyed by the Mechanism