Insulin increases the capacity of a cell to transport glucose by

Question

Quizplus · Accepted Answer

Insulin stimulates the translocation of GLUT 4 vesicles from intracellular location to the plasma membrane, thereby increasing the capacity of a cell to transport glucose. This is achieved through the activation of a signaling pathway that triggers the fusion of GLUT 4-containing vesicles with the plasma membrane, which leads to increased glucose uptake by the cell. Insulin does not directly stimulate the formation of more GLUT 4 vesicles or the activity of other glucose transporters such as GLUTs 1 and 3. However, insulin can indirectly stimulate the activity of hexokinase, which is a key enzyme involved in glucose metabolism, by promoting the delivery of glucose to the cell.

Insulin Increases the Capacity of a Cell to Transport Glucose