Triose phosphate isomerase is diffusion controlled.

Question

Quizplus · Accepted Answer

Triose phosphate isomerase catalyzes the interconversion of dihydroxyacetone phosphate (DHAP) and glyceraldehyde 3-phosphate (G3P) in the glycolytic pathway. The enzyme has a very high catalytic rate, close to the diffusion-controlled limit, meaning that the rate of the reaction is mainly limited by the diffusion of the substrate to the enzyme's active site rather than by the enzyme's catalytic efficiency. Therefore, it is classified as diffusion-controlled.

Triose Phosphate Isomerase Is Diffusion Controlled