Deficiencies in G6PDH (glucose-6-phosphate dehydrogenase)in humans causes

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Deficiencies in G6PDH lead to varying degrees of hemolytic anemia due to the inability of red blood cells to protect themselves from oxidative stress. However, it also confers increased resistance to malaria since the parasite is vulnerable to oxidative stress. The lack of NADPH in many cells is a secondary effect of G6PDH deficiency as NADPH is required for several cellular processes such as detoxification of free radicals.

Deficiencies in G6PDH (Glucose-6-Phosphate Dehydrogenase)in Humans Causes