Which statement is true about lactate dehydrogenase and malate dehydrogenase?
A)Both enzymes are highly specific for their own substrates.
B)A single amino acid change can convert lactate dehydrogenase to a malate dehydrogenase.
C)The naturally occurring enzymes do not have much sequence similarity,but do have closely related three-dimensional structures.
D)All of the above.

Question

Quizplus · Accepted Answer

All of the statements are true. Both enzymes are highly specific for their substrates, indicating the precision of enzyme-substrate interactions. A single amino acid change can indeed convert lactate dehydrogenase to malate dehydrogenase, demonstrating the critical role of specific amino acids in enzyme function. Despite low sequence similarity, these enzymes have closely related three-dimensional structures, highlighting the importance of structure in enzymatic activity.

Which Statement Is True About Lactate Dehydrogenase and Malate Dehydrogenase