Regulation of acetyl CoA-carboxylase is accomplished by

Question

Quizplus · Accepted Answer

Acetyl CoA-carboxylase is regulated by multiple mechanisms. It is inhibited by high levels of fatty acyl CoA, which is an indicator of sufficient fatty acid stores in the cell. In addition, citrate can activate acetyl CoA-carboxylase in vitro by allosterically binding to it and stabilizing its polymerized form. Finally, glucagon signaling can lead to the inactivation of acetyl CoA-carboxylase, promoting the breakdown of stored fatty acids for energy production. Therefore, the best choice is D, which includes all of the above regulatory mechanisms.

Regulation of Acetyl CoA-Carboxylase Is Accomplished by