In eukaryotes all enzymes for the biosynthesis of the pyrimidine nucleotides occur exclusively in the cytosol.

Question

Quizplus · Accepted Answer

While it is true that some enzymes involved in pyrimidine biosynthesis occur in the cytosol, others occur in the mitochondria or the nucleus. For example, the enzyme dihydroorotate dehydrogenase, which catalyzes a key step in pyrimidine biosynthesis, is located in the inner mitochondrial membrane.

In Eukaryotes All Enzymes for the Biosynthesis of the Pyrimidine