Histones associate with DNA primarily through ________.
A)hydrogen bonding
B)hydrophobic interactions with the exposed bases in the major groove
C)ionic interactions with the phosphate groups
D)disulfide linkages

Question

Quizplus · Accepted Answer

Histones have a net positive charge due to their high content of basic amino acids such as lysine and arginine. They primarily associate with the negatively charged phosphate groups of DNA through ionic interactions.

Histones Associate with DNA Primarily Through ________