Alkaline hydrolysis of RNA produces a mixture of 2' and 3' - nucleotides.Hydrolysis by RNase A produces only the 3'-nucleotides.

Question

Quizplus · Accepted Answer

Alkaline hydrolysis of RNA breaks the phosphodiester bonds, resulting in a mixture of 2' and 3'-nucleotides. On the other hand, RNase A cleaves RNA specifically at the 3'-end of the nucleotides, resulting in only 3'-nucleotides. Therefore, the statement is true.

Alkaline Hydrolysis of RNA Produces a Mixture of 2' and 3