Fragments on the lagging strand are joined by the enzyme ________.
A)DNA polymerase I
B)DNA synthase
C)DNA primosome
D)DNA ligase

Question

Quizplus · Accepted Answer

Fragments on the lagging strand are joined by the enzyme DNA ligase, which seals the sugar-phosphate backbone of the Okazaki fragments by forming a phosphodiester bond between the adjacent nucleotides. DNA polymerase I removes the RNA primers from the Okazaki fragments and fills in the gaps with DNA nucleotides. DNA synthase and DNA primosome are not enzymes involved in DNA replication.

Fragments on the Lagging Strand Are Joined by the Enzyme