What distinguishes direct repair from other DNA repair mechanisms?

Question

Quizplus · Accepted Answer

Direct repair does not involve the removal and replacement of a damaged nucleotide, but instead repairs the nucleotide in place without breaking the phosphodiester backbone of the DNA molecule.

Answer: B
 Unlike some other DNA repair mechanisms, such as nucleotide excision repair (NER) which requires activation by light or other chemicals, direct repair proteins can recognize and repair DNA damage without external signals.

Answer: D
 Direct repair systems are capable of recognizing and repairing specific types of damage, such as the removal of a methyl group from a guanine nucleotide, without replacing the entire nucleotide. This is distinct from other mechanisms such as base-excision repair, which involves the removal and replacement of a single nucleotide. Direct repair is a simpler mechanism that works to correct specific types of DNA damage without the need for extensive nucleotide replacement.

What Distinguishes Direct Repair from Other DNA Repair Mechanisms