Which statement is not true about the binding of TBP (TATA binding protein)?
A)The TBP subunit is only required for the initiation of transcription of class II genes.
B)The binding of TBP to DNA distorts the DNA out of the standard B-DNA form.
C)Contacts between TBP and DNA are mainly in the minor groove.
D)TBP forms a saddle-shaped molecular clamp that surrounds DNA at the TATA box.

Question

Quizplus · Accepted Answer

The statement that the TBP subunit is only required for the initiation of transcription of class II genes is not true. TBP is also required for the transcription of class III genes, which have internal promoters.

Which Statement Is Not True About the Binding of TBP