The correct order for the formation of the prokaryotic 70S initiation complex is:
A)50S → IF-1,IF-2 → mRNA → fMet-tRNAfmet → 30S
B)30S → IF-1,IF-3 → fMet-tRNAfmet → IF-2 → mRNA → 50S
C)30S → IF-1,IF-3 → IF-2 → fMet-tRNAfmet → mRNA → 50S
D)30S → IF-1,IF-2 → IF-3 → fMet-tRNAfmet → mRNA → 50S

Question

Quizplus · Accepted Answer

The correct order for the formation of the prokaryotic 70S initiation complex is: 30S → IF-1, IF-3 → IF-2 → fMet-tRNAfmet → mRNA → 50S. The 30S ribosome subunit binds to the mRNA and then the initiator fMet-tRNAfmet binds to the P-site of the ribosome. Initiation factors (IF-1, IF-2, and IF-3) then help in the binding of the 50S subunit to form the complete 70S initiation complex. In this way, the correct order for the formation of the prokaryotic 70S initiation complex is 30S → IF-1, IF-3 → IF-2 → fMet-tRNAfmet → mRNA → 50S.

The Correct Order for the Formation of the Prokaryotic 70S