The pH inside cells is normally near pH 7.At pH 7 which statement is true about the charges (ionization state)of the α-Carboxyl and α-Amino groups of an amino acid?

Question

Quizplus · Accepted Answer

At pH 7, the α-carboxyl group of an amino acid tends to lose a proton, becoming negatively charged (1-), while the α-amino group tends to gain a proton, becoming positively charged (1+). This is because the pKa of the carboxyl group is typically around 2, and the pKa of the amino group is around 9, making them deprotonated and protonated, respectively, at physiological pH.

The PH Inside Cells Is Normally near PH 7