An enzyme is irreversibly inhibited by diisopropylfluorophosphate (DFP).What does this show?
A)The enzyme has been denatured by DFP.
B)Serine is likely an important residue in the active site.
C)DFP is an allosteric modulator of the enzyme.
D)DFP is an analog of the enzyme's substrate.

Question

Quizplus · Accepted Answer

DFP irreversibly inhibits enzymes that contain a serine residue in their active site. This indicates that the serine residue is likely important for the enzyme's catalytic activity.

An Enzyme Is Irreversibly Inhibited by Diisopropylfluorophosphate (DFP)