Protein A has four identical subunits,each of which binds one molecule of ligand Y.The binding of one molecule of Y to one of the subunits induces a conformational change in neighboring subunits that enhances the binding of additional units of Y.This is an example of ________.
A)negative cooperativity
B)competitive activation
C)symmetry-driven binding
D)the sequential theory

Question

Quizplus · Accepted Answer

This is an example of the sequential theory, which posits that the binding of a ligand to one site on a multimeric protein can affect the binding properties of other sites on the same protein, often enhancing the binding affinity for additional ligand molecules. This is in contrast to negative cooperativity, where binding of a ligand decreases the affinity at other sites, and competitive activation and symmetry-driven binding, which are not standard terms used to describe this phenomenon.

Protein a Has Four Identical Subunits,each of Which Binds One