At sufficiently high substrate concentration all types of reversible inhibition can be overwhelmed.At high substrate concentration the enzyme will be saturated and the reaction will proceed at the same maximum velocity as in the absence of inhibitor.

Question

Quizplus · Accepted Answer

At high substrate concentrations, competitive inhibitors can be overcome because they compete with the substrate for the active site, but non-competitive and uncompetitive inhibitors cannot be fully overcome by increasing substrate concentration, as they do not compete for the active site and affect the enzyme activity differently.

At Sufficiently High Substrate Concentration All Types of Reversible Inhibition