A thermodynamic pit occurs when
A)ES is not very stable.
B)ES forms faster than it dissociates.
C)ES is highly stable.
D)S is not bound tightly to an enzyme.
E)S is positioned incorrectly to the enzyme.

Question

Quizplus · Accepted Answer

A thermodynamic pit occurs when the enzyme-substrate complex (ES) is highly stable, meaning that the substrate is bound so tightly to the enzyme that it is not easily converted to product, leading to a decrease in reaction rate.

A Thermodynamic Pit Occurs When