The role of serine at the active site of serine proteases is to act as a(n)________ catalyst,while the histidine residue serves as a(n)________ catalyst.
A)strong;weak
B)weak;strong
C)acid-base;covalent
D)covalent;acid-base
E)anionic;ionic

Question

Quizplus · Accepted Answer

Serine acts as a covalent catalyst by forming a temporary covalent bond with the substrate, while histidine serves as an acid-base catalyst by donating and accepting protons during the reaction process in serine proteases.

The Role of Serine at the Active Site of Serine