Cocaine causes the neurotransmitter dopamine to remain at the site of the synapse longer than it normally would. Cocaine thus inhibits the process called:

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Cocaine inhibits the process of reuptake, where neurotransmitters like dopamine are taken back up into the presynaptic neuron. This results in an accumulation of dopamine at the synapse, leading to the pleasurable and reinforcing effects of the drug.

Cocaine Causes the Neurotransmitter Dopamine to Remain at the Site