If a tumor secretes high levels of osteoclast-activating factor, which of the following would you expect to occur as a result of this condition?
A) increases in blood levels of calcium
B) bone fragility
C) decreased bone density
D) increased osteoclast activity
E) All of the answers are correct.

Question

Quizplus · Accepted Answer

Osteoclast-activating factor (OAF) stimulates the activity of osteoclasts, which are cells responsible for bone resorption. Therefore, high levels of OAF would lead to the breakdown of bone tissue, resulting in decreased bone density and bone fragility. This process releases calcium from the bone into the bloodstream, leading to an increase in blood levels of calcium. Hence, all the options are correct.

If a Tumor Secretes High Levels of Osteoclast-Activating Factor, Which