Tay-Sachs disease is a human genetic abnormality that results in cells accumulating and becoming clogged with very large and complex lipids. Which cellular organelle must be involved in this condition?
A) the endoplasmic reticulum
B) the Golgi apparatus
C) the lysosome
D) mitochondria
E) membrane-bound ribosomes

Question

Quizplus · Accepted Answer

Lysosomes are the organelles responsible for breaking down and recycling cellular components, including lipids. In Tay-Sachs disease, a deficiency in the enzyme hexosaminidase A leads to the accumulation of gangliosides (a type of lipid) in the lysosomes of nerve cells, causing neurological symptoms.

Tay-Sachs Disease Is a Human Genetic Abnormality That Results in Cells