Which of the following is an example of cooperativity?
A)the binding of an end product of a metabolic pathway to the first enzyme that acts in the pathway
B)protein function at one site affected by binding at another of its active sites
C)a molecule binding at one unit of a tetramer allowing faster binding at each of the other three
D)the effect of increasing temperature on the rate of an enzymatic reaction
E)binding of an ATP molecule along with one of the substrate molecules in an active site

Question

Quizplus · Accepted Answer

Cooperativity is when binding at one site of a protein affects binding or activity at another site. In this case, the binding of a molecule at one unit of a tetramer (a protein made up of four subunits) affects binding at the other three subunits, allowing for faster binding overall. This is an example of positive cooperativity.

Which of the Following Is an Example of Cooperativity