Among enzymes, kinases catalyze phosphorylation, while phosphatases catalyze removal of phosphate(s). A cell's use of these enzymes can therefore function as an on-off switch for various processes. Which of the following is probably involved?
A)the change in a protein's charge leading to a conformational change
B)the change in a protein's charge leading to cleavage
C)a change in the optimal pH at which a reaction will occur
D)a change in the optimal temperature at which a reaction will occur
E)the excision of one or more peptides

Question

Quizplus · Accepted Answer

Phosphorylation, which is catalyzed by kinases, involves the addition of a phosphate group to a protein. This can change the charge of the protein and lead to a conformational change, which in turn can turn a process on or off. Similarly, removal of a phosphate group by phosphatases can change the charge and conformation of a protein, thereby regulating a biological process. Therefore, option A is the best answer. The other options (B, C, D, and E) are not directly related to the action of kinases and phosphatases.

Among Enzymes, Kinases Catalyze Phosphorylation, While Phosphatases Catalyze Removal of Phosphate(s)