Taxol is an anticancer drug extracted from the Pacific yew tree. In animal cells, taxol disrupts microtubule formation by binding to microtubules and accelerating their assembly from the protein precursor, tubulin. Surprisingly, this stops mitosis. Specifically, taxol must affect
A)the fibers of the mitotic spindle.
B)anaphase.
C)formation of the centrioles.
D)chromatid assembly.
E)the S phase of the cell cycle.

Question

Quizplus · Accepted Answer

Taxol disrupts microtubule formation by binding to microtubules and accelerating their assembly from the protein precursor, tubulin. Since microtubules are the fibers of the mitotic spindle, disrupting their formation would affect the spindle and stop mitosis.

Taxol Is an Anticancer Drug Extracted from the Pacific Yew