Which of the Following Accounts for Someone Who Has Had

Which of the following accounts for someone who has had a herpesvirus-mediated cold sore or genital sore getting flare-ups for the rest of life?

A) re-infection by a closely related herpesvirus of a different strain
B) re-infection by the same herpesvirus strain
C) co-infection with an unrelated virus that causes the same symptoms
D) copies of the herpesvirus genome permanently maintained in host nuclei
E) copies of the herpesvirus genome permanently maintained in host cell cytoplasm