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Question 87

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The following questions are based on the description below.
Rose-picker's disease is caused by the yeast, Sporothrix schenkii. The yeast grows on the exteriors of rose-bush thorns. If a human gets pricked by such a thorn, the yeasts can be introduced under the skin. The yeasts then assume a hyphal morphology and grow along the interiors of lymphatic vessels until they reach a lymph node. This often results in the accumulation of pus in the lymph node, which subsequently ulcerates through the skin surface, and drains.
-Humans have immune systems in which lymph nodes are important, because many phagocytes and lymphocytes reside therein. Given that a successful infection by S. schenkii damages lymph nodes themselves, which of these is most probable?


A) The hyphae secrete antibiotics, which increases the ability of the infected human to tolerate the fungus.
B) Their conversion from yeast to hyphal morphology allows such fast growth that the body's defenses are at least temporarily overwhelmed.
C) Defensive cells of humans cannot detect foreign cells that are covered with cell walls composed of cellulose.
D) Given that most fungal pathogens attack plants, human defenses are simply not adapted to seek out and destroy fungi.
E) Given that most fungal pathogens of humans infect only the skin, human defenses are not adapted to seek out and destroy systemic fungal infections.

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