Use the Following Information to Answer the Following Questions

Use the following information to answer the following questions.
Mouse mutations can affect an animal's appetite and eating habits. The ob gene produces a satiety factor (the hormone leptin) . The db gene product is required to respond to the satiety factor (the leptin receptor) .
-Most obese humans produce normal or increased levels of leptin without satiety. Which might provide an answer to at least some human obesity if a means to do so is found?

A) supplementary leptin
B) inactivation of leptin
C) overexpression of the leptin receptor gene
D) activation of receptors for leptin
E) inhibition of leptin receptors