While more Alzheimer's disease is not hereditary, there is one subset of cases, called Familial Alzheimer's Disease (FAD)that can be seen to be transmitted through pedigrees. FAD has earlier age of onset but is otherwise similar. Which of the following groups of genes would you expect to be involved?
A)genes for amyloid or amyloid cleaving enzymes
B)genes for dopamine precursors
C)genes for biogenic amines
D)genes for premature aging
E)genes for microtubules

Question

Quizplus · Accepted Answer

Familial Alzheimer's Disease (FAD) is known to be caused by mutations in genes involved in the production and processing of amyloid protein. These include genes for amyloid precursor protein (APP) as well as genes for enzymes that cleave APP, such as presenilin 1 and presenilin 2. Mutations in these genes lead to an overproduction of amyloid protein, which can form into plaques in the brain and lead to the degeneration and death of neurons.

While More Alzheimer's Disease Is Not Hereditary, There Is One