A clinic nurse is assessing an adolescent male patient who has been receiving androgen therapy for hypogonadism via a transdermal patch. The patient's last clinic visit was 4 weeks earlier. Which part of the interval history is of most concern to the nurse?

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Patients receiving testosterone may experience edema secondary to sodium and water retention. Treatment involves discontinuing the drug and giving diuretics if needed. Patients may develop a sensitivity rash at the site of transdermal application. Gynecomastia is an expected effect, as is the development of acne.

A Clinic Nurse Is Assessing an Adolescent Male Patient Who