The nurse is administering medications to the patient who is in liver failure resulting from end-stage cirrhosis. The nurse is aware that patients with liver failure would most likely have problems with which pharmacokinetic phase?

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The liver is the organ that is most responsible for drug metabolism. Decreased liver function most strongly affects the metabolism of a drug. Liver function does not affect the absorption and distribution of a drug. Excretion is affected only because decreased liver function may not trAnswerform drugs into water-soluble substances for elimination via the kidneys, but that is not the best Answerwer for this question.

The Nurse Is Administering Medications to the Patient Who Is