Which of the following is thought to be the major factor in the pathogenesis of liver injury?

Question

Quizplus · Accepted Answer

The timing and histologic appearance of hepatocyte injury in viral hepatitis suggest that immune responses,particularly cytotoxic T cell responses to viral antigens expressed on hepatocyte cell membranes,may be the major effectors of injury.Other proinflammatory cytokines,natural killer cell activity,and antibody-dependent cellular cytotoxicity also may play modulating roles in cell injury and inflammation during acute viral hepatitis infection.

Which of the Following Is Thought to Be the Major