Which of the following is the most common cause of secondary adrenal insufficiency?

Question

Quizplus · Accepted Answer

Suppression of the HPA axis by exogenous or endogenous glucocorticoids is the most common cause of secondary adrenal insufficiency.The secretion of cortisol is directly dependent on the level of circulating ACTH.As plasma cortisol level increases,the production of ACTH decreases by virtue of negative feedback to the pituitary and hypothalamus.With the administration of corticosteroids,the feedback system senses the elevated plasma steroid levels and inhibits ACTH production,which in turn suppresses adrenal production of cortisol.

Which of the Following Is the Most Common Cause of Secondary