If the level of anticoagulation of a transplant patient is greater than that for an international normalized ratio (INR)of ___,the dosage of medication may need to be reduced by the patient's physician.

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If the INR is greater than 3.5,the dosage of the medication may need to be reduced.At least 3 to 4 days are required for the effect of the reduced dosage to lower the PT.When the patient's INR has been appropriately reduced,the surgery can be performed.After surgery,the dentist must be prepared to deal with excessive bleeding,by use of splints,thrombin,hemostatic agents,or antifibrinolytic agents.

If the Level of Anticoagulation of a Transplant Patient Is