What Does This Statement Mean

What does this statement mean?
"The potentially adverse action of the released catecholamines on cardiovascular function in the patient with clinically significant heart or blood vessel disease warrants the inclusion of vasoconstrictors in the local anesthetic solution."

A) The release of catecholamines has the potential to adversely affect a patient's cardiovascular function.
B) Without adequate control of pain, sedation and stress reduction are impossible to achieve; however, use of local anesthetic plus a vasoconstrictor will help to ensure adequate pain control.
C) A patient with significant heart or blood vessel disease should always have a local anesthetic plus a vasoconstrictor solution.
D) A patient with significant heart or blood vessel disease should never have a local anesthetic plus a vasoconstrictor solution.