During cell injury caused by hypoxia, why is there an increase in the osmotic pressure within the cell?

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Quizplus · Accepted Answer

In hypoxic injury, movement of fluid and ions into the cell is associated with acute failure of metabolism and loss of ATP production. Normally the pump that transports sodium ions out of the cell is maintained by the presence of ATP and ATPase, the active-transport enzyme. In metabolic failure caused by hypoxia, reduced ATP and ATPase permit sodium to accumulate in the cell, whereas potassium diffuses outward. The increase of intracellular sodium increases osmotic pressure, which draws more water into the cell (transport mechanisms are described in Chapter 1).

During Cell Injury Caused by Hypoxia, Why Is There an Increase