One systemic manifestation of an acute inflammatory response is fever that is produced by:
A)endogenous pyrogens acting directly on the hypothalamus.
B)exogenous pyrogens acting directly on the hypothalamus.
C)immune complexes acting indirectly on the hypothalamus.
D)cytokines acting indirectly on the hypothalamus.

Question

Quizplus · Accepted Answer

There is little evidence that exogenous pyrogens cause fever directly. Such pyrogens indirectly affect the hypothalamus through endogenous pyrogens released by cells of the host.

One Systemic Manifestation of an Acute Inflammatory Response Is Fever