Heparin-induced thrombocytopenia (HIT) is described as a(n):
A)IgG immune-mediated adverse drug reaction that reduces circulating platelets.
B)hematologic reaction to heparin in which the bone marrow is unable to produce sufficient platelets to meet the body's needs.
C)IgE-mediated allergic drug reaction that reduces circulating platelets.
D)cell-mediated drug reaction in which macrophages process the heparin and platelet complexes that are then destroyed by activated cytotoxic T cells.

Question

Quizplus · Accepted Answer

Heparin is a common cause of drug-induced thrombocytopenia. HIT is an immune-mediated, adverse drug reaction caused by IgG antibodies that leads to increased platelet consumption and a decrease in platelet counts.

Heparin-Induced Thrombocytopenia (HIT) Is Described as A(n)