In ARDS, inflammatory mediators such as proteolytic enzymes, oxygen free radicals, prostaglandins, leukotrienes, and platelet-activating factor are released by:
A)complement cascade.
B)mast cells.
C)macrophages.
D)neutrophils.

Question

Quizplus · Accepted Answer

The role of neutrophils is central to the development of ARDS. Activated neutrophils release a battery of inflammatory mediators, among them proteolytic enzymes, oxygen free radicals (superoxide radicals, hydrogen peroxide, hydroxyl radicals), arachidonic acid metabolites (prostaglandins, thromboxanes, leukotrienes), and platelet-activating factor. These mediators cause extensive damage of the alveolocapillary membrane and greatly increase capillary membrane permeability

In ARDS, Inflammatory Mediators Such as Proteolytic Enzymes, Oxygen Free