Which statement is false about the skeletal alterations caused by chronic renal failure? When the glomerular filtration rate (GFR) declines to 25% of normal
A)parathyroid hormone (PTH) is no longer effective in maintaining serum phosphate levels.
B)the parathyroid gland is no longer able to secrete sufficient parathyroid hormone (PTH).
C)there is impaired synthesis of 1,25-vitamin D3, which reduces intestinal absorption of calcium.
D)there is impaired synthesis of 1,25-vitamin D3, which impairs the effectiveness of calcium and phosphate resorption from bone by parathyroid hormone (PTH).

Question

Quizplus · Accepted Answer

Bone and skeletal changes develop with alterations in calcium and phosphate metabolism (Table 36-16). These changes begin when GFR decreases to 25% or less. The combined effect of hyperparathyroidism and vitamin D deficiency can result in renal osteodystrophies (i.e., osteomalacia and osteitis fibrosa with increased risk for fractures.

Which Statement Is False About the Skeletal Alterations Caused by Chronic