Which of the following leads to a decrease in ESV?
A)acetylcholine
B)preload
C)afterload
D)parasympathetic activity
E)vagal activity

Question

Quizplus · Accepted Answer

Preload refers to the amount of blood that fills the ventricle during diastole. An increase in preload will lead to an increase in end-diastolic volume (EDV), which in turn leads to an increase in end-systolic volume (ESV) due to the Frank-Starling mechanism. Conversely, a decrease in preload will lead to a decrease in ESV. Acetylcholine, parasympathetic activity, and vagal activity are all related to decrease heart rate and have minimal direct effect on stroke volume. Afterload refers to the resistance that the left ventricle must overcome to eject blood from the heart, an increase in afterload will increase ESV.

Which of the Following Leads to a Decrease in ESV