Lipophilic hormones must interact with __________ prior to gene activation.
A)membrane receptors
B)G-proteins
C)intracellular receptors
D)adenylate cyclase
E)both b and d

Question

Quizplus · Accepted Answer

Lipophilic hormones, such as steroid hormones, can diffuse across the cell membrane and bind to intracellular receptors located in the cytoplasm or nucleus. The hormone-receptor complex then enters the nucleus and interacts directly with DNA to activate or repress specific genes. Therefore, lipophilic hormones must interact with intracellular receptors prior to gene activation. Membrane receptors, G-proteins, and adenylate cyclase are involved in the signaling pathways of lipophobic hormones, such as adrenaline and glucagon, which cannot cross the cell membrane and instead bind to receptors on the cell surface.

Lipophilic Hormones Must Interact with __________ Prior to Gene Activation